Sometimes solving the biggest challenges means thinking small – very small.Ìý
At no bigger than a pea, our Amplatzerâ„¢ Piccolo is one of the smallest heart devices ever. Most importantly, Piccolo is the first U.S. approved device small enough to close a hole in the heart of a premature infant weighing as little as 700 grams (about 1.5 pounds). And because Piccolo is a minimally-invasive device, it can eliminate the need for riskier surgery.Ìý
A breakthrough that for thousands of future newborn lives, will keep open a lifetime of possibility.
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1. Krasuki, R.A. (2006). Patent ductus arteriosus closure. Journal of Interventional Cardiology, 19 (5 Suppl), S60-S66.
2. Dice JE, Bhatia J. Patent ductus arteriosus: an overview. J Pediatr Pharmacol Ther 2007;12(3):138-46.
For U.S. Important Safety Information about the Amplatzer Piccolo Occluder, visit:
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